منابع مشابه
Protein structure networks.
The application of the field of network science to the scientific disciplines of structural biology and biochemistry, have yielded important new insights into the nature and determinants of protein structures, function, dynamics and the folding process. Advancements in further understanding protein relationships through network science have also reshaped the way we view the connectivity of prot...
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Background: Prediction of the protein localization is among the most important issues in the bioinformatics that is used for the prediction of the proteins in the cells and organelles such as mitochondria. In this study, several machine learning algorithms are applied for the prediction of the intracellular protein locations. These algorithms use the features extracted from pro...
متن کاملProtein Secondary Structure Modelling with Probabilistic Networks
In this paper we study the performance of probabilistic networks in the context of protein sequence analysis in molecular biology. Speci cally, we report the results of our initial experiments applying this framework to the problem of protein secondary structure prediction. One of the main advantages of the probabilistic approach we describe here is our ability to perform detailed experiments w...
متن کاملProtein Secondary-Structure Modeling with Probabilistic Networks
In this paper we study the performance of probabilistic networks in the context of protein sequence analysis in molecular biology. Specifically, we report the results of our initial experiments applying this framework to the problem of protein secondary structure prediction. One of the main advantages of the probabilistic approach we describe here is our ability to perform detailed experiments ...
متن کاملOptimized Null Model for Protein Structure Networks
Much attention has recently been given to the statistical significance of topological features observed in biological networks. Here, we consider residue interaction graphs (RIGs) as network representations of protein structures with residues as nodes and inter-residue interactions as edges. Degree-preserving randomized models have been widely used for this purpose in biomolecular networks. How...
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ژورنال
عنوان ژورنال: Briefings in Functional Genomics
سال: 2012
ISSN: 2041-2649,2041-2657
DOI: 10.1093/bfgp/els039